-
20151805(IL-1+beta): Initial periodontal therapy reduced systemic and local 25-hydroxy vitamin D(3) and interleukin-1beta in patients with aggressive periodontitis.
All patients received initial periodontal therapy.
-
20192617(Tumor Necrosis Factor-alpha): Serum levels of cytokines in subjects with generalized chronic and aggressive periodontitis before and after non-surgical periodontal therapy: a pilot study.
RESULTS : After therapy , both periodontitis groups demonstrated a significant improvement in clinical periodontal status (P (0.05).
-
18771364(Tumor Necrosis Factor-alpha): Anti-TNF-alpha immunotherapy is associated with increased gingival inflammation without clinical attachment loss in subjects with rheumatoid arthritis.
Therefore , TNF-alpha blockade could be beneficial in the treatment of periodontitis.
-
19186970(Interferon-gamma): Levels of interferon-gamma and transcription factor T-bet in progressive periodontal lesions in patients with chronic periodontitis.
The aims of this work were to determine IFN-gamma levels in samples of gingival crevicular fluid (GCF) and to determine IFN-gamma and transcription factor T-bet expression in gingival tissue from patients undergoing the progression of chronic periodontitis.
-
11752460(STAT1): T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells.
T-bet , a recently discovered member of the T-box transcription factor family , has been reported to play a critical role in this process , promoting IFN-gamma production.