IL-1 beta→Interferon-gamma→c-jun

• 20157206(IL-1+beta): [Correlative analysis between indices of rheological particularities of blood, IL-1beta and lipid profile in patients with chronic cor pulmonary]

  Working-out the algorithm of the diagnosis of cor pulmonary on the grounds of mathematical modeling and analysis of laboratory indices.

• 14680077(Interferon-gamma): Does interferon-gamma improve pulmonary function in idiopathic pulmonary fibrosis?

  Idiopathic pulmonary fibrosis (IPF) is a disease with progressive and devastating deterioration of lung function and a fatal prognosis , despite aggressive therapeutic attempts , which , in the majority of cases are futile.

• 12375272(c-jun): MAP kinase activation and apoptosis in lung tissues from patients with idiopathic pulmonary fibrosis.

  Three major MAP kinases (MAPKs) , including extracellular signal-regulated kinase (ERK) , c-jun N-terminal kinase (JNK) , and p38 kinase (p38 MAPK) , are involved in the regulation of lung inflammation and injury.