glutamine→Glutamic Acid→Glutamic Acid→pyruvate kinase

• 16097425(glutamine): Lack of cardioprotection from metabolic support with glutamine or glutamate in a porcine coronary occlusion model.

  We investigated the effect of glutamine or glutamate , given during reperfusion , on resulting infarct size and hemodynamic recovery.

• 2867519(Glutamic Acid): Function and metabolism of dog heart in ischemia and in subsequent reperfusion: effect of exogenous glutamic acid.

  When reperfusion was carried out during glutamic acid infusion there was a significantly enhanced recovery in cardiac function.

• 2867848(Glutamic Acid): Cardiac metabolism and performance during L-glutamic acid infusion in postoperative cardiac failure.

  Intravenous infusion of L-glutamic acid results in the augmentation of the cardiac output and an improvement of the circulation in patients with postoperative cardiac failure.

• 15588442(pyruvate kinase): Plasma concentrations of tumour dimeric pyruvate kinase are increased in patients with chronic cardiac failure.

  The aim of the study was to assess the effect of chronic cardiac failure (CCF) on circulating plasma concentrations of tumor metabolic marker dimeric pyruvate kinase type M2 (M2-PK).