pyruvate kinase→Pyruvate Kinase→Pyruvate Kinase→Pyruvate Kinase→glutamine

• 16375581(pyruvate kinase): Plasma levels of tumor M2-pyruvate kinase should not be used as a tumor marker for hematological malignancies and solid tumors.

  Hence , it was suggested that circulating levels of the so-called tumor M2-pyruvate kinase (Tu M2-PK) could be used as a tumor marker for monitoring systemic therapies of various solid tumors.

• 11326672(Pyruvate Kinase): Tumor type M2 pyruvate kinase expression in advanced breast cancer.

  Recently , a high validity correlation of the tumor M2 pyruvate kinase (Tu M2-PK) isoenzyme in comparison to standard tumor markers has been demonstrated in solid tumors.

• 2971267(Pyruvate Kinase): Heterogeneity of glycolytic enzyme activity and isozyme composition of pyruvate kinase in breast cancer.

  Heterogeneity also existed in isozyme composition of pyruvate kinase.

• 178389(Pyruvate Kinase): [Pyruvate kinase activity in the liver of rats with induced tumors].

  M-isozyme pyruvate kinase activity proved to be elevated in the liver of rats with hepatoma induced by p-dimethylaminoazobenzene.

• 15962369(glutamine): Glutamine is highly effective in preventing in vivo cobalt-induced oxidative stress in rat liver.

  To evaluate the in vivo effect of glutamine on cobalt-generated oxidative stress and (HO-1) induction in rat liver.