Pyruvate kinase (PK) from a moderate thermophile , Bacillus stearothermophilus (BstPK) , is an allosteric enzyme activated by AMP and ribose 5-phosphate but not by fructose 1,6-bisphosphate (FBP).
Pyruvate kinase from rabbit muscle has been crystallized in a form suitable for high resolution X-ray analysis.
In kidney medulla of rabbits with alloxan diabetes the pyruvate kinase activity was increased by 39 % as compared with control animals.
The hepatic pyruvate kinase activity markedly decreased when rats were made diabetic by alloxan injection.
To evaluate the effects of glutamine (L-Gln) or whey-protein supplementation on CD4 + and CD8 + lymphocytes in alloxan-induced diabetic rats.