pyruvate kinase→Pyruvate Kinase→Pyruvate Kinase→glutamine

• 17550844(pyruvate kinase): Transgenic rescue of hemolytic anemia due to red blood cell pyruvate kinase deficiency.

  Red blood cell pyruvate kinase (R-PK) deficiency is the most common glycolytic enzyme defect associated with hereditary non-spherocytic hemolytic anemia.

• 3674096(Pyruvate Kinase): Elevated pyruvate kinase activity in patients with hemolytic anemia due to red cell pyruvate kinase "deficiency".

  Two patients with non-spherocytic hemolytic anemia were found to have elevated red blood cell pyruvate kinase activities commensurate with the decreased mean red cell age , but the residual pyruvate kinase had marked kinetic abnormalities.

• 178389(Pyruvate Kinase): [Pyruvate kinase activity in the liver of rats with induced tumors].

  M-isozyme pyruvate kinase activity proved to be elevated in the liver of rats with hepatoma induced by p-dimethylaminoazobenzene.

• 15962369(glutamine): Glutamine is highly effective in preventing in vivo cobalt-induced oxidative stress in rat liver.

  To evaluate the in vivo effect of glutamine on cobalt-generated oxidative stress and (HO-1) induction in rat liver.