pyruvate kinase→Neurotransmitter Agents→Pyruvate Kinase→Pyruvate Kinase→glutamine

• 17649802(pyruvate kinase): Fecal pyruvate kinase-M2 (tumor M2-PK) measurement: a new screening concept for colorectal cancer.

  Colonoscopy is purportedly the best screening tool for CRC.

• 16929400(Neurotransmitter Agents): Prospective multicenter evaluation of fecal tumor pyruvate kinase type M2 (M2-PK) as a screening biomarker for colorectal neoplasia.

  It 's a direct target of several oncoproteins ; the determination of fecal tumor pyruvate kinase type M2 (M2-PK) might be another promising tool for colorectal cancer (CRC) screening.

• 9329624(Pyruvate Kinase): Quantification of tumor type M2 pyruvate kinase (Tu M2-PK) in human carcinomas.

  Proliferating and tumor cells express a certain isoenzyme of pyruvate kinase , called PK type M2.

• 2854097(Pyruvate Kinase): Human M2-type pyruvate kinase: cDNA cloning, chromosomal assignment and expression in hepatoma.

  Two overlapping clones , covering the entire coding sequence of human M2-type pyruvate kinase (PK) cDNA , were isolated and sequenced.

• 1460020(glutamine): Molecular cloning, cDNA sequence, and bacterial expression of human glutamine:fructose-6-phosphate amidotransferase.

  On the basis of these results we conclude that : 1) functional human GFAT protein was expressed , and 2) the cloned human cDNA encodes both the catalytic and regulatory domains of GFAT since the recombinant GFAT was sensitive to UDP-GlcNAc.