pyruvate kinase→Neurotransmitter Agents→Pyruvate Kinase→Pyruvate Kinase→Iron→glutamine

• 17649802(pyruvate kinase): Fecal pyruvate kinase-M2 (tumor M2-PK) measurement: a new screening concept for colorectal cancer.

  Therefore evaluation of additional screening tools is of great interest.

• 16929400(Neurotransmitter Agents): Prospective multicenter evaluation of fecal tumor pyruvate kinase type M2 (M2-PK) as a screening biomarker for colorectal neoplasia.

  In this study , we have evaluated fecal M2-PK as a screening biomarker for colorectal neoplasia.

• 2498076(Pyruvate Kinase): Comparative study of human M2-type pyruvate kinases isolated from human leukocytes and erythrocytes of a patient with red cell pyruvate kinase hyperactivity.

  M2-type pyruvate kinases (M2-PK) have been isolated from human leukocytes and from the erythrocytes of a patient with erythrocyte PK hyperactivity.

• 5921478(Pyruvate Kinase): Three cases of hemolytic anemia with erythrocyte pyruvate kinase deficiency in Alberta.

  Erythrocyte pyruvate kinase (PK) activity was determined by the lactate dehydrogenase-coupled spectrophotometric assay.

• 7976118(Iron): Erythropoietin in the treatment of iron overload in a patient with hemolytic anemia and pyruvate kinase deficiency.

  Iron overload has been reported with pyruvate kinase deficiency.

• 15719403(glutamine): MARS treatment for a patient presenting with acquired hepatic glutamine synthetase deficiency after orthotopic liver transplantation.

  On investigation he was found to have acquired hepatic glutamine synthetase deficiency , a rare condition that occurs after organ transplantations.