pyruvate kinase→Pyruvate Kinase→Pyruvate Kinase→glutamine

• 17784868(pyruvate kinase): Faecal dimeric M2 pyruvate kinase in colorectal cancer and polyps correlates with tumour staging and surgical intervention.

  A dimeric form of pyruvate kinase isoenzyme (tumor M2-PK) is predominantly found in highly proliferating cells.

• 15588442(Pyruvate Kinase): Plasma concentrations of tumour dimeric pyruvate kinase are increased in patients with chronic cardiac failure.

  The aim of the study was to assess the effect of chronic cardiac failure (CCF) on circulating plasma concentrations of tumor metabolic marker dimeric pyruvate kinase type M2 (M2-PK).

• 1159538(Pyruvate Kinase): Increased activity of pyruvate kinase in plasma of vitamin E-deficient rats.

  The effect of dietary vitamin E on activities of pyruvate kinase and lactate dehydrogenase was studied in tissues of rats.

• 8987589(glutamine): Effect of dietary L-glutamine on the hepatotoxic action of D-galactosamine in rats.

  Rats fed with 20 % casein diets containing 10 % free amino acids were injected with GaIN , and the serum aspartate aminotransferase , alanine aminotransferase and lactate dehydrogenase activities and the hepatic glycogen content were assayed 20 hours after the injection.