Explore Transcription Factors and Their Target Genes

For a selected transcription factor, Expresso allows the user to explore its corresponding target genes and binding motifs. The potential gene targets can be limited by the E-value option, which is the level of conservation in the motif. Further explanation about the E-value can be found in this reference paper. From the dialog box below, you can select transcription factors included in Expresso and set the E-value for motif finding(the default setting is 0.05).*

*you can find more information about E-value for motif finding in this reference: Anton Valouev et al. “Genome-wide analysis of transcription factor binding sites based on ChIP-Seq data” Nature Methods 5, 829 - 834 (2008)

E-value for motif: